Dr Animesh Samanta
Associate Professor School of Natural Sciences
School of Natural Sciences
Email: animesh.samanta@snu.edu.in
My research focuses on the design and development of functional fluorogenic materials with diverse structural architectures for advanced diagnostics and therapeutic applications. A key area of our work involves activity-based chemosensors and molecular probes for detecting biologically and environme...
Research Overview
My research focuses on the design and development of functional fluorogenic materials with diverse structural architectures for advanced diagnostics and therapeutic applications. A key area of our work involves activity-based chemosensors and molecular probes for detecting biologically and environmentally relevant analytes, including toxic substances in food and water. We also design fluorescent probes for monitoring microenvironments,-such as pH, viscosity, polarity, and temperature,-and for detecting reactive carbon, oxygen, and nitrogen species at the subcellular level. These tools help us study disease progression and identify early biomarkers for conditions such as diabetes, Alzheimer's disease, Parkinson's disease, and cancer. Additionally, our research includes nanoparticle-based multimodal imaging platforms to integrate diagnostic imaging with therapeutic functions like photodynamic therapy (PDT), photothermal therapy (PTT), and chemotherapy with a particular emphasis on cancer for precision medicine. This interdisciplinary approach bridges synthetic chemistry, bioimaging, and materials science to address pressing challenges in healthcare and environmental monitoring. Know more: Click here
Education
2024 Jan - Present Associate Professor, Department of Chemistry, School of Natural Sciences (SoNS), Shiv Nadar University, Uttar Pradesh, India-201314 2019 May - 2023 Dec Assistant Professor, Department of Chemistry, Shiv Nadar University 2016 Nov-2019May Ramanujan Fellow, CSIR -NIIST 2015 Aug -2016 Sep Research Fellow, NUS, Dept. Biomedical Engineering 2012 Mar-2015Aug Research Fellow, Singapore Bioimaging Consortium, A*STAR, Singapore 2008 Jan -2012 Mar Ph.D. in chemistry, National University of Singapore, (NUS) 2005 Aug -2007 Jun M.Sc., Indian Institute of Technology Madras (IIT Madras), India 2002-2005 B.Sc. (Honors); Midnapore College, Vidyasagar University, India 2000-2002 Higher Secondary (12th), West Bengal Council of Higher Secondary Education
Experience
Category Details Current Position Associate Professor, Department of Chemistry, School of Natural Sciences, Shiv Nadar University (Jan 2024 - Present) Previous Position Assistant Professor, Shiv Nadar University (May 2019 - Dec 2023) Research Interests Synthetic chemistry, chemical biology, nanotechnology; development of activity-based fluorescent probes (ABFPs) for: Biomolecule and pollutant sensing Monitoring microenvironments (pH, viscosity, polarity, temperature) Detection of reactive carbon, oxygen, and nitrogen species (RCS, ROS, RNS) at the subcellular level Past Fellowships Ramanujan Fellow, CSIR-NIIST (Dec 2016 - May 2019) Research Fellow, National University of Singapore, Biomedical Engineering (Aug 2015 - Sep 2016) Research Fellow, Singapore Bioimaging Consortium, A*STAR (Mar 2012 - Aug 2015) Expertise Nanoparticle-based multimodal imaging, luminescence, and SERS; cancer diagnostics and therapy including PDT, PTT, and chemo-theranostics Education Ph.D. in Chemistry, National University of Singapore (2008-2012) M.Sc. in Chemistry, IIT Madras (2005-2007) Publications 67 research articles, 3 book chapters Patents 2 patents Ph.D. Supervision 4 completed, 3 ongoing Research Grants 4 grants received (including 1 ongoing from Shiv Nadar Foundation)
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| 1 |
Article
Molecular Detection Sensitivity at the Sub-Atto-Molar Limit Using Plasmonic Perovskite Nanoplates
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Samanta, S.; Paul, S.; Bora, E.; Gaur, T.; Guchhait, N.; Gómez-Graña, S.; Sarker, D.; Debnath, T. | ACS Applied Nano Materials, 8(46), 22389-22399 | 2025 | 0 |
| 2 |
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Engineering fluorescent probes for tracking lysosomal pH in β-amyloid-induced microglial activation and phagocytosis
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Munan, S.; Mondal, A.; Tiwari, S.; Yadav, R.; Pareek, N.; Samanta, A. | Journal of Materials Chemistry B, 13(43), 14091-14100 | 2025 | 1 |
| 3 |
Article
In-Vitro Anti-cancer Therapeutic Effects of 2D-Ti3C2-MXene-Coated Hesperetin (Ti3C2_H) against Cervical Cancer Cells
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Deb, V.K.; Yadav, R.; Samanta, A.; Kumar, K.; Jain, U. | Journal of Inorganic and Organometallic Polymers and Materials, 35(10), 8202-8218 | 2025 | 1 |
| 4 |
Article
A bright, water-soluble far-red fluorescent probe for detecting thiols in both mitochondria and lysosomes in living cells
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Mondal, A.; Pareek, N.; Khan, A.R.; Sahoo, S.K.; Samanta, A.; Dutta, S. | Analyst, 150(18), 4155-4168 | 2025 | 1 |
| 5 |
Article
Effect of N-quaternization on crystal and electronic structures of E-pyridylvinyl benzothiazoles – Photophysical and electrochemical properties, and cytotoxicity studies
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Baskar, S.; Yadav, R.; Shanmugam, G.; Sarkar, K.; Samanta, A.; Kole, G.K. | Journal of Photochemistry and Photobiology A: Chemistry, 466 | 2025 | 1 |
| 6 |
Article
Oxidative Rearrangement of 3-Aryl Azo Indoles in Water: Synthesis of C3-Oxo-C2-Amino Indoles and their Application as Fluorophores for Lipid Droplet Detection
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Prabakar, T.; Ambastha, P.; Yadav, R.; Samanta, A.; Ravva, M.K.; Munshi, P.; Sen, S. | Advanced Synthesis and Catalysis, 367(14) | 2025 | 0 |
| 7 |
Article
Plexciton Dynamics in Au-Hybrid CsPbBr3Perovskite Nanoplatelets
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Bora, E.; Das, J.P.; Samanta, S.; Kumar, A.; Debnath, T. | Journal of Physical Chemistry Letters, 16(28), 7134-7139 | 2025 | 1 |
| 8 |
Article
Unusually Stable Synthetic Diheme Bis-Fe(IV)oxo: An Intermediate in Diheme Enzymes MauG and BthA
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Samanta, D.; Sarkar, S.; Singh, D.; Samanta, S.; Manna, S.; Dutta Dubey, K.D.; Dey, A.; Shaik, S.; Rath, S.P. | Journal of the American Chemical Society, 147(26), 22562-22571 | 2025 | 1 |
| 9 |
Article
A Dual-Emission Probe for Discriminating Cys/Hcy from GSH/H2S in Human Blood Serum and Live Cells
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Khan, A.R.; Pareek, N.; Mondal, A.; Samanta, A.; Dutta, S. | ChemistrySelect, 10(24) | 2025 | 1 |
| 10 |
Article
Nonradiative Energy Transfer between CsPbBr3 Nanoplatelets and AgInS2 Quantum Dots
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Samanta, S.; Shah, S.H.; Bora, E.; Debnath, T. | Inorganic Chemistry, 64(22), 11177-11183 | 2025 | 0 |
| 11 |
Article
3D printed cellulose nanofiber-reinforced and iron-crosslinked double network hydrogel composites for tissue engineering applications: Mechanical properties and cellular viability
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Goyal, R.; Mahapatra, S.N.; Yadav, R.; Mitra, S.; Samanta, A.; Kumar, A.; Lochab, B. | Bioprinting, 46 | 2025 | 5 |
| 12 |
Article
Optimization of ZnO films for the development of ZnO/NiO heterojunction solar cells
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Samanta, A.; Mondal, P. | Journal of Materials Science: Materials in Electronics, 36(10) | 2025 | 2 |
| 13 |
Article Open access
A Fluorescent Probe Differentiates Apoptosis from Cysteine-Deprivation Ferroptosis through Imaging of Viscosity and Lipid Droplets
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Pareek, N.; Yadav, R.; Munan, S.; Baruah, M.; Samanta, A. | Chemistry - A European Journal, 31(13) | 2025 | 2 |
| 14 |
Article
Tailoring sputter grown NiOx layer by synergistic surface passivation for efficient perovskite solar cells
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Yadav, K.; Samanta, A.; Ankita; Tarun; Das, S.; Kanjilal, A.; Pandey, U.K. | Solar Energy, 288 | 2025 | 3 |
| 15 |
Article Open access
A simple yet effective H2S-activated fluorogenic probe for precise imaging of hepatitis and arthritis in situ
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Liang, W.; Bian, Y.; Samanta, A.; Chen, X.; Yu, X.; Zheng, Y.; Gao, X.; Su, D. | BMEMat, 3(1) | 2025 | 7 |
| 16 |
Article
Tetrasubstituted imidazole-based multifunctional fluorophores: trace water detection and lipid droplet (LD) imaging studies
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Zafar, M.M.; Yadav, R.; Singh, A.; Tyagi, N.; Samanta, A.; Mishra, R.K. | Chemical Communications, 61(50), 9091-9094 | 2025 | 0 |
| 17 |
Review Open access
Molecular Imaging of Nitric Oxide Surrogates with Organelle-Specific Fluorescent Probes
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Yadav, R.; SanuKhan, R.; Kalita, N.; Mendiratta, S.; Sivaramakrishnan, S.; Murugan, S.; Samanta, A. | Chemistry - An Asian Journal, 20(4) | 2025 | 1 |
| 18 |
Article
Methionine-Derived Fluorescent Probes Targeting Mitochondria: A Tool for Real-Time Oxidative Stress Monitoring in Live Cells
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Pareek, N.; Kalita, N.; Pandey, R.; Samanta, A. | ChemBioChem, 26(5) | 2025 | 1 |
| 19 |
Article
Revealing plasmonic TiN films with low power radio-frequency magnetron sputtering technique
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Samanta, A.; Chattaraj, A.; Matam, S.; Walczak, L.; Sagdeo, A.; Kanjilal, A. | Thin Solid Films, 811 | 2025 | 2 |
| 20 |
Article Open access
Pyrene Based Schiff Base for Cascade Fluorescent “On-Off” Detection of Aluminium(III) and Fluoride Ions and its Applications in Live Cells Imaging
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Bhardwaj, K.; Yadav, R.; Samanta, A.; Jangir, R.; Jali, B.R.; Kumar, S.K.A.; Sahoo, S.K. | Chemistry and Biodiversity, 22(2) | 2025 | 3 |
| 21 |
Article
G6PD deficiency mediated impairment of iNOS and lysosomal acidification affecting phagocytotic clearance in microglia in response to SARS-CoV-2
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Mondal, A.; Munan, S.; Saxena, I.; Mukherjee, S.; Upadhyay, P.; Gupta, N.; Dar, W.; Samanta, A.; Singh, S.; Pati, S. | Biochimica et Biophysica Acta - Molecular Basis of Disease, 1870(7) | 2024 | 2 |
| 22 |
Article Open access
Computational investigation of novel synthetic analogs of C-1′β substituted remdesivir against RNA-dependent RNA-polymerase of SARS-CoV-2
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Cardoza, S.; Singh, A.; Sur, S.; Singh, M.; Dutta Dubey, K.D.; Samanta, S.K.; Mandal, A.; Tandon, V. | Heliyon, 10(17) | 2024 | 2 |
| 23 |
Article
9-Phenanthrenylvinyl-4′-pyridine and Its N-Methylated Analogue: From the Crystal Structure and Photoisomerization to Photophysical and Electrochemical Properties and Application in Bioimaging
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Kannan, T.S.; Yadav, R.; Rukmini Sarma, M.; Pramanik, G.; Samanta, A.; Kole, G.K. | Crystal Growth and Design, 24(17), 7235-7245 | 2024 | 4 |
| 24 |
Article
Quinoline based viologen as a multifunctional organic material – From crystal structures to photophysical and electrochemical properties, and application in DNA sensing and bioimaging
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Kannan, T.S.; Munan, S.; Samanta, A.; Kole, G.K. | Journal of Photochemistry and Photobiology A: Chemistry, 454 | 2024 | 5 |
| 25 |
Article
IndiFluors: A New Full-Visible Color-Tunable Donor-Acceptor-Donor (D1-A-D2) Fluorophore Family for Ratiometric pH Imaging during Mitophagy
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Munan, S.; Kottarathil, S.; Joseph, M.M.; Jana, A.; Ali, M.; Mapa, K.; Maiti, K.K.; Samanta, A. | ACS Sensors, 9(7), 3502-3510 | 2024 | 22 |
| 26 |
Article
Exploring Efficiency Improvement by Introducing Ge in CsSnI3 Perovskite Solar Cells: Computational Approach
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Samanta, A.; Kumar, V.; Kanjilal, A. | Journal of Electronic Materials, 53(7), 4272-4286 | 2024 | 6 |
| 27 |
Article
Unique Synthetic Strategy for Probing in Situ Lysosomal NO for Screening Neuroinflammatory Phenotypes against SARS-CoV-2 RNA in Phagocytotic Microglia
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Munan, S.; Mondal, A.; Singh, S.; Pati, S.; Samanta, A. | Analytical Chemistry, 96(19), 7479-7486 | 2024 | 10 |
| 28 |
Review
Unraveling Ferroptosis Mechanisms: Tracking Cellular Viscosity with Small Molecular Fluorescent Probes
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Pareek, N.; Mendiratta, S.; Kalita, N.; Sivaramakrishnan, S.; Khan, R.S.; Samanta, A. | Chemistry - An Asian Journal, 19(8) | 2024 | 13 |
| 29 |
Article Open access
Two-step growth of alumina nanoparticle decorated graphene oxide surfaces: Effect on photocatalytic activity
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Verma, S.; Santra, B.; Chattaraj, A.; Samanta, A.; Chowdhury, S.; Matam, S.; Sagdeo, A.; Kanjilal, A.; Katharria, Y.S. | Journal of Applied Physics, 135(6) | 2024 | 3 |
| 30 |
Article
Synthesis and Optical Properties of Potassium-Based Wide-Bandgap Mixed–Halide Perovskite KPbF2Cl Nanorods
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Samanta, A.; Chattaraj, A.; Santra, B.; Sinha, J.; Kumar, V.; Kanjilal, A. | Physica Status Solidi - Rapid Research Letters, 18(2) | 2024 | 1 |
| 31 |
Book chapter
Advanced Strategies in Designing Fluorescent Probes for Reactive Oxygen Species Analysis
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Baruah, M.; Kalita, N.; Samanta, A. | Fluorescent Chemosensing and Bioimaging, 166-204 | 2024 | 0 |
| 32 |
Book chapter
Enhancing Biomolecule Recognition Through Cellular Imaging Using Functional Fluorophores
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Pareek, N.; Yadav, R.; Samanta, A. | Fluorescent Chemosensing and Bioimaging, 205-229 | 2024 | 0 |
| 33 |
Article
Chronological development of functional fluorophores for bio-imaging
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Munan, S.; Chang, Y.-T.; Samanta, A. | Chemical Communications, 60(5), 501-521 | 2023 | 26 |
| 34 |
Article
Solid-State Photodimerization Reaction with Photosalient Effect and Photophysical and Electrochemical Properties of N-Methylated 1-Naphthylvinyl-4-Quinoline
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Kannan, T.S.; Munan, S.; Murugavel, M.; Samanta, A.; Kole, G.K. | Crystal Growth and Design, 23(11), 8261-8269 | 2023 | 11 |
| 35 |
Article
Polarity-Driven Two-Photon Fluorescent Probe for Monitoring the Perturbation in Lipid Droplet Levels during Mitochondrial Dysfunction and Acute Pancreatitis
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Biswas, S.; Baruah, M.; Shil, A.; Sarkar, S.; Ali, M.; Samanta, A.; Bhuniya, S. | ACS Sensors, 8(10), 3793-3803 | 2023 | 29 |
| 36 |
Article Open access
Metal-free synthesis and study of glycine betaine derivatives in water for antimicrobial and anticancer applications
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Rath, S.; Maiti, D.; Modi, M.; Pal, P.; Munan, S.; Mohanty, B.; Bhatia, A.; Bhowal, R.; Priyadarshini, R.; Samanta, A.; Munshi, P.; Sen, S. | iScience, 26(8) | 2023 | 3 |
| 37 |
Review
Ratiometric fluorescent probes for pH mapping in cellular organelles
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Munan, S.; Yadav, R.; Pareek, N.; Samanta, A. | Analyst, 148(18), 4242-4262 | 2023 | 45 |
| 38 |
Article
A Systematic Design and Synthesis of PET-based Fluorescent Probes for Monitoring pH During Mitophagy
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Yadav, R.; Munan, S.; Ali, M.; Mapa, K.; Samanta, A. | Chemistry - An Asian Journal, 18(12) | 2023 | 9 |
| 39 |
Article Open access
Esterase Specific Fluorescent Probe: Mechanistic Understanding Using QM/MM Calculation and Cell States Discrimination
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Yadav, R.; Munan, S.; Kardam, V.; Dutta Dubey, K.D.; Samanta, A. | Chemistry - A European Journal, 29(32) | 2023 | 13 |
| 40 |
Article Open access
A Ratiometric Fluorescent Probe for Hypochlorite and Lipid Droplets to Monitor Oxidative Stress
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Baruah, M.; Jana, A.; Pareek, N.; Singh, S.; Samanta, A. | Biosensors, 13(6) | 2023 | 14 |
| 41 |
Article
A Photoinduced Electron Transfer-Based Hypochlorite-Specific Fluorescent Probe for Selective Imaging of Proinflammatory M1 in a Rheumatoid Arthritis Model
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Baruah, M.; Kwon, H.-Y.; Cho, H.; Chang, Y.-T.; Samanta, A. | Analytical Chemistry, 95(8), 4147-4154 | 2023 | 41 |
| 42 |
Article
Light induced diversity-oriented synthesis (DOS) library of annulated indolizine fluorophores for imaging non-lysosomal lipid droplets (LDs)
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Maiti, D.; Munan, S.; Singh, S.; Das, R.; Samanta, A.; Sen, S. | Journal of Materials Chemistry B, 11(10), 2191-2199 | 2023 | 13 |
| 43 |
Article
Depletion Driven Assembly of Ultrasmall Metal Nanoclusters: From Kinetically Arrested Assemblies to Thermodynamically Stable, Spherical Superclusters
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Bera, D.; Baruah, M.; Dehury, A.K.; Samanta, A.; Chaudhary, Y.S.; Goswami, N. | Journal of Physical Chemistry Letters, 13(40), 9411-9421 | 2022 | 15 |
| 44 |
Article
PET- and ICT-Based Ratiometric Probe: An Unusual Phenomenon of Morpholine-Conjugated Fluorophore for Mitochondrial pH Mapping during Mitophagy
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Munan, S.; Ali, M.; Yadav, R.; Mapa, K.; Samanta, A. | Analytical Chemistry, 94(33), 11633-11642 | 2022 | 51 |
| 45 |
Review
Activity-Based Fluorescent Probes for Sensing and Imaging of Reactive Carbonyl Species (RCSs)
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Jana, A.; Baruah, M.; Samanta, A. | Chemistry - An Asian Journal, 17(8) | 2022 | 15 |
| 46 |
Article
An efficient molecular luminophore based on tetraphenylethylene (TPE) enabling intracellular detection and therapeutic benefits of hydrogen sulfide in Alzheimer's disease
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Ramya, A.N.; Joseph, M.M.; Karunakaran, V.; Ahammed, C.V.S.; Samanta, A.; Maiti, K.K. | Sensors and Actuators B: Chemical, 355 | 2022 | 41 |
| 47 |
Article
An efficient PeT based fluorescent probe for mapping mitochondrial oxidative stress produced via the Nox2 pathway
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Baruah, M.; Jana, A.; Ali, M.; Mapa, K.; Samanta, A. | Journal of Materials Chemistry B, 10(13), 2230-2237 | 2022 | 20 |
| 48 |
Article
ICT based water-soluble fluorescent probe for discriminating mono and dicarbonyl species and analysis in foods
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Jana, A.; Baruah, M.; Munan, S.; Samanta, A. | Chemical Communications, 57(52), 6380-6383 | 2021 | 48 |
| 49 |
Article
Reaction of the Decaosmium Carbido Cluster [Os10(µ6-C)(CO)24]2− with Halostibines
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Barik, C.K.; Ganguly, R.; Li, Y.; Samanta, S.; Leong, W.K. | Journal of Cluster Science, 32(4), 929-935 | 2021 | 2 |
| 50 |
Article
A single benzene fluorescent probe for efficient formaldehyde sensing in living cells using glutathione as an amplifier
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Jana, A.; Joseph, M.M.; Munan, S.; K, S.; Maiti, K.K.; Samanta, A. | Journal of Photochemistry and Photobiology B: Biology, 214 | 2021 | 25 |
Project details will be updated soon.
Research contributions aligned with UN Sustainable Development Goals:
3
Good Health and Well-being
6
Clean Water and Sanitation
7
Affordable and Clean Energy
9
Industry, Innovation and Infrastructure
| Type | Title | Status | Filed Date | Inventors |
|---|---|---|---|---|
| Patent | A Lysosome specific Nitric Oxide Probe for Neuroinflammation and process of synthesis thereof | Published | 12/06/2023 | Animesh Samanta Subrata Munan Soumya Pati Abir Mondal Shailja Singh |
Awards & Honors
- Year Name of Awards and Certificates Awarding Agency/Institutes 2024 Shiv Nadar Foundation Inter Institution Collaboration Grants 2024. PI: Dr. Animesh Samanta and Co-PI: Dr. Rudra Nayan Das, Dr. Sudipta Som, Dr. Tatini Rakshit SNF collaborative grant 2023 UPCST research grant, Sanction amount: 9 lakhs. PI: Dr. Soumya Pati and Co-PI: Dr. Animesh Samanta, grant number Council of Science and Technology U.P. India 2023 Guest Editor in special issue, Chemosensors MDPI Publisher 2022 Lifetime member of Chemical Research Society of India (CRSI) CRSI, India 2022 Affiliated member of Royal Society of chemistry RSC, UK 2021 Core Research Grant 2021, CRG/2021/002313 DST-SERB, Govt. of India 2021 Young Investigator award 2021 Shiv Nadar University 2016-2021 Ramanujan Fellowship, Award No. SB/S2/RJN-148/2015 DST-SERB, Govt. of India 2012 DST-INSPIRE Faculty Fellowship, Award No. IFA12-CH-87 DST-INSPIRE, Govt. of India 2012 First prize Johnson & Johnson Ser. Inc. Asia Outstanding Graduate Thesis Award in Bio-tech. Johnson and Johnson Services Inc. Asia 2007 Graduate Aptitude Test Examination (GATE) All India Rank: 150 MHRD, Govt. of India 2007 CSIR-Junior Research Fellowship (JRF) CSIR, Govt. of India 2006 R Padmanavan Memorial Prize I.I.T. Madras
Professional Memberships
- No memberships listed.
Additional information will be updated soon.